Cytokines 2024 & KAI 2024

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Scientific Program

Scientific Program

All Room
Room A
Room B
Room C

October 20(Sun) 15:10-16:50	Symposium 1 mRNA Vaccine and Immunity		Room A
Speaker(s)		TBC Annette Vogel (BioNTech SE, DEU)
		B cell responses to vaccination: Lessons from the SARS-CoV-2 pandemic Ali Ellebedy (Washington Univ., USA)
		TBC Galit Alter (Moderna, USA)

October 20(Sun) 15:10-16:50	Symposium 2 IFNs and Inflammation		Room B
Speaker(s)		Positive and Negative Regulation of Interferon Signaling and Antiviral Immunity Curt Horvath (Northwestern Univ., USA)
		Molecular mechanisms of innate immunity and inflammation in health and disease Thirumala-Devi Kanneganti (St. Jude Children's Hospital, USA)
		Regulation of cancer immunity, spatial organization, and immunotherapy by interferons David G Brooks (Univ. of Toronto, CAN)

October 20(Sun) 16:50-17:40	Keynote		Room A
Speaker(s)		Type 2 Cytokines: a story of Macrophages, Matrix & Metazoan Parasites Judith Allen (The Univ. of Manchester, GBR)

October 21(Mon) 08:30-10:10	Symposium 3 Host-Microbiota Interaction		Room A
Speaker(s)		Wild-derived microbiota regulate host immune responses and disease outcome in preclinical models Barbara Rehermann (NIH, USA)
Speaker(s)		Microbiome Therapeutics for Inflammatory Disorders and Cancer Sin-Hyeog Im (POSTECH, KOR)

October 21(Mon) 08:30-10:10	Symposium 4 B cell and Cytokines		Room B
Speaker(s)		IL-4 and germinal center B cell selection Marion Pepper (Univ. of Washington, USA)
		Title: B cell immune responses in complex microenvironment Ziv Shulman (Weizmann Institute of Science, ISR)
		The impact of type I interferon dynamics on memory B cell subsets during infection Kim Good-Jacobson (Monash Univ., AUS)

October 21(Mon) 08:30-10:10	Symposium 5 KAI-AKIA		Room C
Speaker(s)		Dissecting host immune responses in situ Jun Huh (Harvard Univ., USA)
		CD103 preconditions naïve CD8 T cells for their acquisition of effector phenotype and function Jung-Hyun Park (NIH/NCI, USA)
		TBC
		TBC

October 21(Mon) 10:40-12:00	Symposium 6 Trained Immunity and Cytokines		Room A
Speaker(s)		Central Trained Immunity and Chronic Inflammation George Hajishengallis (Univ. of Pennsylvania, USA)
Speaker(s)		Innate Immune Memory and the Aging Eye Przemyslaw Sapieha (Centre de recherche HMR, FRA)

October 21(Mon) 10:40-12:00	Symposium 7 Mucosal Immunity		Room B
Speaker(s)		Microbiota-regulation of Tumor-Associated Macrophages Jorge Henao-Mejia (Univ. of Pennsylvania, USA)
Speaker(s)		Microbiota and immune responses in the stomach are involved in controlling various diseases Naoko Satoh-Takayama (RIKEN, JPN)

October 21(Mon) 10:40-12:00	Symposium 8 T cell Homeostasis and Cytokines (Charles D. Surh Memorial Session)		Room C
Speaker(s)		Fixing to generate new T cells (lessons learned from Charlie Surh, about golf, wine & cytokines) Juan Carlos Zuniga-Pflucker (Univ. of Toronto, CAN)
Speaker(s)		Subsetting and shaping naive CD8 T cell pools with complex effector codes Jae Ho Cho (Chonnam Univ, KOR)

October 21(Mon) 16:20-18:00	Symposium 9 Tumor Immunology and Immunotherapy		Room A
Speaker(s)		Control of cytokine signaling to enhance efficacy and safety of CAR-T cell therapy Yuki Kagoya (Keio Univ., JPN)
		Shared mechanisms of Anti-PD1 efficacy in tumor, and toxicity in tissue Niroshana Anandasabapathy (Cornell Univ., USA)
		Functional Identification and Therapeutic Targeting of Cancer Neoantigens Stephen Schoenberger (La Jolla Institute for Immunology, USA)

October 21(Mon) 16:20-18:00	Symposium 10 Infection and Immunity		Room B
Speaker(s)		Differential innate antiviral signaling in human and bat cells Karen Mossman (McMaster Univ., CAN)
		Inflammasome sensing in inflammation and cancer Si Ming Man (Australia National Univ., AUS)
		Regulation of IL-15-induced NK-like activation of CD8+ T cells in viral infection Eui-Cheol Shin (KAIST, KOR)

October 21(Mon) 16:20-18:00	Guest Symposium Predicting virus associated inflammatory disease severity in children with laboratory diagnostics and artificial intelligence- PreVAIL kIds experience with SARS-CoV-2 infection syndrome including MIS-C		Room C
Speaker(s)		Analytics approaches to evaluate the contribution of biomarkers integrated into clinical prediction models Cedric Manlhiot (Johns Hopkins University, USA)
		ML derived unique cytokine/chemokine biosignature of MIS-C across SARS-CoV-2 variants Ananth Annapragada (Texas Children's Hospital, USA)
		Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C) Juan Salazar (Connecticut Children's Hospital, USA)
		Multisystem inflammatory syndrome in children (MIS-C) induces a Toll-like receptor-tolerant phenotype in peripheral blood cells that is genetically modulated Maria Gennaro (Rutgers University, USA)
		Diagnosing and predicting risk in children with SARS-CoV-2 related illness Jane Burns (University of California, San Diego, USA)
		Host-based clinical assays for diagnosis and severity prediction of COVID-19 associated clinical syndromes including MIS-C Charles Chiu (University of California, San Francisco, USA)

October 22(Tue) 08:30-10:10	Symposium 11 Cytokine Engineering		Room A
Speaker(s)		Molecular modulation of interleukin-2 for next-generation immunotherapy Onur Boyman (Univ. of Zurich, CHE)
		Protein engineering efforts enable the production of IFNλ4, the solution of the receptor complex by cryoEM, and provide insights into its differential activity Juan Mendoza (Univ Chicago, USA)
		Targeting tumor microenvironment with engineered cytokines Yang-Xin Fu (Tsinghua Univ., CHN)

October 22(Tue) 08:30-10:10	Symposium 12 Immune Regulation of Inflammatory Diseases		Room B
Speaker(s)		Transcription factor NFAT5 is essential to chronic inflammatory diseases Wan-Uk Kim (Catholic Univ., KOR)
		Metabolic Checkpoints in Autoimmune Tissue Inflammation Cornelia M. Weyand (Mayo Clinic, USA)
		Role of MIF in the Glucocorticoid Regulation of Immune Responsiveness Richard J. Bucala (Yale Univ. School of Medicine, USA)

October 22(Tue) 10:40-12:00	Symposium 13 Cytokines and Myeloid Cells		Room A
Speaker(s)		Neutrophil heterogeneity at steady state and stress conditions Lai Guan Ng (Singapore Immunology Network(SIgN), A*STAR, SGP)
Speaker(s)		Transcriptional and spatial control of macrophages in cancer Renato Ostuni (Università Vita-Salute San Raffaele, ITA)

October 22(Tue) 10:40-12:00	Symposium 14 Cytokines and CD8 T cell Immunity		Room B
Speaker(s)		T cell differentiation and function in chronic infection and cancer Axel Kallies (Univ. of Melbourne, AUS)
Speaker(s)		Costimulation modulates the PD-1+ CD8 T cells beyond priming Alice Kamphorst (Mount Sainai, USA)

October 22(Tue) 10:40-12:00	Symposium 15 Immune Regulation of Tissue Repair		Room C
Speaker(s)		Fibroblast orchestration of tissue resident lymphocytes in disease and aging Tien Peng (Univ. of California, San Francisco, USA)
Speaker(s)		Immune-mediated mechanisms of adaptive and maladaptive tissue responses Shruti Naik (New York Univ., USA)

October 22(Tue) 16:20-18:00	Symposium 16 Type 2 Immunity and Airway Diseases		Room A
Speaker(s)		Regulating type 2 cytokine production from T follicular helper cells Stephanie Eisenbarth (Northwestern Univ., USA)
		ILCs at the Crossroads: Understanding their Influence in Type 2 Immunity and Airway Disorders Hye-Young Kim (Seoul National Univ., KOR)
		The regulation and role lung resident and lymphoid T follicular helper cells in allergic airways disease James Harker (Imperial College London, GBR)

October 22(Tue) 16:20-18:00	Symposium 17 Clinical Immunology of Autoimmune Diseases		Room B
Speaker(s)		The role of cytokine receptors in identifying T cell subsets in health and disease Insoo Kang (Yale Univ. School of Medicine, USA)
		Mechanism-based cytokine-targeting therapies and precision medicine in rheumatic diseases Yoshiya Tanaka (Univ. of Occupational and Environmental Health, JPN)
		Integrative Functional Genomics Reveals the Determinants of Age/Autoimmune-Associated B Cells (ABCs) Nan Shen (Shanghai Jiao Tong Univ. School of Medicine, CHN)

October 22(Tue) 16:20-18:00	Guest Symposium Lambda IFN		Room C
Speaker(s)		IFN-λ controls intestinal repair in IBD Achille Broggi (CIML, FRA)
		STING dependent induction of type III IFN subtypes Megan Stanifer (Univ. of Florida, USA)
		Single cell sequencing of influenza virus infected primary human alveolar macrophages reveals a powerful Interferon Lambda response Rune Hartmann (Aarhus Univ., DNK)
		Viral exploitation of the programmed cell death for evasion of IFN-Lambda immunity Sanghyun Lee (Brown Univ., USA)
		Regulation of antiviral immunity in the intestinal epithelium Tim Nice (OHSU, USA)

October 23(Wed) 08:30-10:10	Symposium 18 Cytokine-blockade Therapy of Human Diseases		Room A
Speaker(s)		Anti-T2 biologics in severe asthma Ian Adcock (Imperial College London, GBR)
		Role of CXCR6+CD4+ Tissue-Resident Memory T Cells in Chronic Allergic Skin Inflammation Kenji Kabashima (Kyoto Univ., JPN)
		The multifaceted contribution of the BAFF/APRIL system to Chronic Lymphocytic Leukemia progression Fabienne Mackay (QIMR Berghofer Medical Research Institute, AUS)

October 23(Wed) 08:30-10:10	Symposium 19 Cytokines in T helper Differentiation and Function		Room B
Speaker(s)		Gene dosage control by multi-enhancer hub formation Golnaz Vahedi (Univ. of Pennsylvania, USA)
		Neuronal Control of Cutaneous Inflammation Daniel Kaplan (Univ. of Pittsburgh, USA)
		Non-canonical regulation of IL-21 bioavailability and activity Di Yu (The Univ. of Queensland, AUS)

October 23(Wed) 13:30-14:30	Keynote		Room A
Speaker(s)		Nucleoside Modified mRNA-LNP Therapeutics Drew Weissman (Univ. of Pennsylvania, USA)

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